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Superhelical duplex destabilization and the recombination position effect.

The susceptibility to recombination of a plasmid inserted into a chromosome varies with its genomic position. This recombination position effect is known to correlate with the average G+C content of the flanking sequences. Here we propose that this effect could be mediated by changes in the suscepti...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Cheryl L Sershen, Joshua C Mell, Sally M Madden, Craig J Benham
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2011-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3111454?pdf=render
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