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Cryogenic, but not hypothermic, preservation disrupts the extracellular matrix of cell sheets

Cell sheet (CS)-based approaches hold significant potential for tissue regeneration, relying on the extracellular matrix (ECM) for success. Like in native tissues, the ECM provides structural and biochemical support for cellular homeostasis and function. Effective preservation strategies that mainta...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sara Freitas-Ribeiro, Andreia F. Carvalho, Daniel B. Rodrigues, Luís Martins, Ricardo A. Pires, Vera M. Mendes, Bruno Manadas, Mariana Jarnalo, Ricardo Horta, Rui L. Reis, Rogério P. Pirraco
Format: Artigo
Sprache:Inglês
Veröffentlicht: KeAi Communications Co., Ltd. 2025-04-01
Schriftenreihe:Bioactive Materials
Schlagworte:
Cell sheets
Extracellular matrix
Biopreservation
Hypothermic preservation
Cryogenic preservation
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2452199X24005565
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