5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy

Abstract At present, there are currently no molecular biomarkers for the early diagnosis of sepsis cardiomyopathy (SCM) in clinical practice. This study focuses on an in-depth examination of the DNA hydroxymethylation profiles within plasma extracellular vesicles and explores potential molecular bio...

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Autori principali:	Baixin Zhen, Zhiling Zhao, Hangyu Chen, Wen Li, Lei Zhang, Xi Zhu, Qinggang Ge, Jian Lin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-07-01
Serie:	Scientific Reports
Soggetti:	Extracellular vesicle 5-hydroxymethylcytosine (5hmC) Septic cardiomyopathy Machine learning Molecular biomarkers
Accesso online:	https://doi.org/10.1038/s41598-025-02489-8
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