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An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques

Ebolavirus vaccines based on several adenoviral vectors have been investigated in preclinical studies and clinical trials. The use of adenovirus serotype 2 as a vector for ebolavirus vaccine has not been reported. Herein, we generated rAd2-ZGP, a recombinant replication-incompetent adenovirus seroty...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yupeng Feng, Chufang Li, Peiyu Hu, Qian Wang, Xuehua Zheng, Yongkun Zhao, Yi Shi, Songtao Yang, Changhua Yi, Ying Feng, Chunxiu Wu, Linbing Qu, Wei Xu, Yao Li, Caijun Sun, Fu Geroge Gao, Xianzhu Xia, Liqiang Feng, Ling Chen
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2018-12-01
Rangatū:Emerging Microbes and Infections
Urunga tuihono:https://www.tandfonline.com/doi/10.1038/s41426-018-0102-5
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