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Artesunate alleviates kidney fibrosis by restoring klotho protein and suppressing Wnt/β-catenin signalling pathway

Chronic kidney disease (CKD) is a global health concern that often progresses to renal failure and premature death. Regardless of etiology of CKD, kidney fibrosis is the main determinant of progressive CKD. Renal fibrosis is characterized by excessive collagen and extracellular-matrix (ECM) depositi...

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Главные авторы: Goran H. Mohammad, Julius Kieswich, Abhishek Kumar, Kieran McCafferty, Ramyangshu Chakraborty, Christoph Thiemermann, Magdi M. Yaqoob
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2025-11-01
Серии:Frontiers in Cell and Developmental Biology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fcell.2025.1688753/full
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