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Mmp2 regulates basement membrane remodeling and dedifferentiation of the visceral musculature during Drosophila metamorphosis

Abstract The basement membrane (BM) is a specialized extracellular matrix that surrounds most tissues and organs. Remodeling of the BM is critical for morphogenesis and to control tissue homeostasis. During Drosophila metamorphosis, most tissues undergo apoptosis and become histolyzed to be replaced...

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Autors principals: Uwe Töpfer, Ina Dahlitz, Anne Holz
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2026-02-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-026-41763-1
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