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Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties

Calreticulin (CRT) is a multifaceted protein, initially discovered as an endoplasmic reticulum (ER) chaperone protein, that is essential in calcium metabolism. Various implications in cancer, early development and immunology have been discovered more recently for CRT, as well as its role as a domina...

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Principais autores: Christophe Moreau, Gianluca Cioci, Marina Iannello, Emmanuelle Laffly, Anne Chouquet, Arturo Ferreira, Nicole M. Thielens, Christine Gaboriaud
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016-11-01
coleção:IUCrJ
Assuntos:
protein structure
molecular recognition
X-ray crystallography
solution scattering
calreticulin
parasites
Acesso em linha:http://scripts.iucr.org/cgi-bin/paper?S2052252516012847
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