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Premature Senescence and Telomere Shortening Induced by Oxidative Stress From Oxalate, Calcium Oxalate Monohydrate, and Urine From Patients With Calcium Oxalate Nephrolithiasis

Oxidative stress, a well-known cause of stress-induced premature senescence (SIPS), is increased in patients with calcium oxalate (CaOx) kidney stones (KS). Oxalate and calcium oxalate monohydrate (COM) induce oxidative stress in renal tubular cells, but to our knowledge, their effect on SIPS has no...

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Principais autores: Kamonchanok Chuenwisad, Pimkanya More-krong, Praween Tubsaeng, Nattida Chotechuang, Monpichar Srisa-Art, Robin James Storer, Chanchai Boonla
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-10-01
coleção:Frontiers in Immunology
Assuntos:
kidney calculi
oxalates
calcium oxalate
cellular senescence
oxidative stress
nephrolithiasis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.696486/full
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