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Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

Abstract The late stage of type 2 diabetes is characterized by secretory dysfunction and increased β‐cell apoptosis, but the underlying mechanisms are not fully understood. The expression and function of secretory carrier membrane protein 5 (SCAMP5) in β‐cells are unclear. The aim is to explore the...

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Principais autores: Yingqi Zhang, Donglan Tang, Chenxi Yang, Chao Lin, Yingyue Yuan, Meiying He, Yiying Chen, Zhuo Mao, Ying Ying, Xiaosong Ma, Xiangchen Kong
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-12-01
coleção:Advanced Science
Assuntos:
β‐cell apoptosis
ChREBP
insulin secretion
SCAMP5
VDAC1
Acesso em linha:https://doi.org/10.1002/advs.202503072
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