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Nanostructured SBA-15 silica as an adjuvant in immunizations with hepatitis B vaccine

Objective: To evaluate the applicability of SBA-15 silica as an adjuvant in immunizations with purified particles of the viral protein HBsAg, the main component of hepatitis B vaccine, Butang®, produced by Instituto Butantan. Methods: BALB/c mice orally or subcutaneously received 0.5 μg of HBsAg ads...

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Auteurs principaux: Karina Scaramuzzi, Denise Cristina André Oliveira, Luciana Vieira Carvalho, Denise Vilarinho Tambourgi, Elisabeth Christina Nunes Tenório, Marisa Rizzi, Juliana Mussalem, Márcia Carvalho de Abreu Fantini, Viviane Fongaro Botosso, Osvaldo Augusto Sant´Anna
Format: Artigo
Langue:Inglês
Publié: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2011-12-01
Collection:Einstein (São Paulo)
Sujets:
Hepatitis B
Oral vaccination
Adjuvants
Immunological memory
Accès en ligne:http://apps.einstein.br/revista/arquivos/PDF/2162-Einstein_v9n4_436-441_eng.pdf
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