Nelfinavir inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly

Abstract Background Antiviral therapies that target herpesviruses are clinically important. Nelfinavir is a protease inhibitor that targets the human immunodeficiency virus (HIV) aspartyl protease. Previous studies demonstrated that this drug could also inhibit Kaposi’s sarcoma-associated herpesviru...

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Autores principales:	Maggie Li, Barbara J. Smith, Jaeyeun Lee, Jennifer Petr, Nicole M. Anders, Robyn Wiseman, Michelle A. Rudek, Richard F. Ambinder, Prashant J. Desai
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-03-01
Colección:	Infectious Agents and Cancer
Materias:	Kaposi’s sarcoma-associated herpesvirus Nelfinavir Virus inhibition Integrated stress response Virus assembly
Acceso en línea:	https://doi.org/10.1186/s13027-024-00566-7
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