Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

BACKGROUND: Zanthoxylum heitzii is a spice used to prepare several dishes and to treat tumors, syphilis, malaria, cardiac palpitations, urogenital infections in the west region of Cameroon, but the antitumor mechanisms and chemical composition are not yet investigated. This study was aimed to determ...

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Autori principali:	Constant Anatole Pieme, Guru Kumar Santosh, Emmanuel Mouafo Tekwu, Tülin Askun, Hatice Aydeniz, Jeanne Yonkeu Ngogang, Shashi Bhushan, Ajit Kumar Saxena
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2014-01-01
Serie:	Biological Research
Soggetti:	Zanthozyllum heitzii Syringic acid Apoptosis HL-60 cells ROS Mitochondrial membrane potential
Accesso online:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100048&lng=en&tlng=en
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