Integrated bioinformatics and experiment validation reveal cuproptosis-related biomarkers and therapeutic targets in sepsis-induced myocardial dysfunction

Abstract Background Sepsis-induced myocardial dysfunction (SIMD) is a serious sepsis complication with high mortality, yet current diagnostic and therapeutic approaches remain limited. The lack of early, specific biomarkers and effective treatments necessitates exploration of novel mechanisms. Recen...

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Detalhes bibliográficos

Principais autores:	Xuemei Shi, Zhonghan Yan, Ruilin Ding, Fenfen Xia, Yan Du, Xiaojie Wang, Qing Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-03-01
coleção:	BMC Infectious Diseases
Assuntos:	Sepsis-induced myocardial dysfunction Cuproptosis-related genes Machine learning Molecular mechanism Biomarkers Therapeutic targets
Acesso em linha:	https://doi.org/10.1186/s12879-025-10822-9
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