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Insight into the Structural Dynamics of the Lysenin During Prepore-to-Pore Transition Using Hydrogen–Deuterium Exchange Mass Spectrometry

Lysenin is a pore-forming toxin of the aerolysin family, which is derived from coelomic fluid of the earthworm <i>Eisenia fetida</i>. Upon binding to sphingomyelin (SM)-containing membranes, lysenin undergoes a series of structural changes promoting the conversion of water-soluble monomers into olig...

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Principais autores: Magdalena Kulma, Michał Dadlez, Katarzyna Kwiatkowska
格式: Artigo
语言:Inglês
出版: MDPI AG 2019-08-01
丛编:Toxins
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在线阅读:https://www.mdpi.com/2072-6651/11/8/462
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