Neurophysiological differences between dexmedetomidine sedation and natural sleep across the rodent lifespan: implications for aging and perioperative brain health

Abstract Purpose Dexmedetomidine is commonly used for its sedative and neuroprotective effects, but its impact on brain activity and sleep architecture is not fully understood. Emerging evidence suggests it may improve postoperative outcomes, particularly in older adults, by promoting sleep-like sta...

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主要な著者:	Morgan J. Siegmann, Daniel P. Zachs, Jonathan D. Kenny, Arianna R. S. Lark, Fayaz A. Mir, Eric D. Melonakos, Mohsen Hozan, Sarah Toledano, Rebecca R. Goldblum, Yang Liu, Michael A. Nolan, Gabriella Cohen, Jinyoung Choi, Christian G. White, Eliza A. Crowley, Abigail Hardy Carpenter, Bryton A. Toro, Channing E. Syme, Emery N. Brown, Christa J. Nehs
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer 2026-01-01
シリーズ:	Anesthesiology and Perioperative Science
主題:	Spike wave discharge Epileptiform activity High voltage spindle
オンライン･アクセス:	https://doi.org/10.1007/s44254-025-00161-y
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