Investigating the mechanism of Xian-ling-lian-xia-fang for inhibiting vasculogenic mimicry in triple negative breast cancer via blocking VEGF/MMPs pathway

Abstract Background Xian-ling-lian-xia-fang (XLLXF), a Chinese medicine decoction, is widely used in the treatment of triple negative breast cancer (TNBC). However, the underlying mechanism of XLLXF in TNBC treatment has not been totally elucidated. Methods Here, network pharmacology and molecular d...

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Principais autores:	Feifei Li, Youyang Shi, Yang Zhang, Xiaojuan Yang, Yi Wang, Kexin Jiang, Ciyi Hua, Chunyu Wu, Chenping Sun, Yuenong Qin, Sheng Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2022-04-01
Serija:	Chinese Medicine
Teme:	Chinese medicine decoction Triple-negative breast cancer Vascular mimicry Network pharmacology Experimental validation
Online dostop:	https://doi.org/10.1186/s13020-022-00597-5
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