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Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance

The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and economic burden in both developing and developed countries. Controlling the spread of HCV through behavioural prevention strategies has met with limited success and vaccine development remains slow. The developm...

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Principais autores: Auda A. Eltahla, Fabio Luciani, Peter A. White, Andrew R. Lloyd, Rowena A. Bull
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-09-01
coleção:Viruses
Assuntos:
hepatitis C virus
polymerase inhibitor
direct-acting antiviral
NS5B
antiviral resistance
RNA dependent RNA polymerase
Acesso em linha:http://www.mdpi.com/1999-4915/7/10/2868
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