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Proteomics and tracer metabolomics link GAPDH ISGylation to glycolytic control

Abstract Background Ubiquitin-like protein ISG15 (interferon-stimulated gene 15) is implicated in the regulation of central carbon metabolism, but conflicting findings across experimental systems limit mechanistic insight. Here, we apply a multi-omics approach in cells ectopically expressing the ISG...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Denzel Eggermont, Lissa Eggermont, Nagihan Aslantaş, Fabien Thery, Katie Boucher, Antje Beling, Bart Ghesquière, Francis Impens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2026-03-01
Saila:Genome Biology
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s13059-026-04034-w
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