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ROLE OF T REGULATORY CELLS IN CHRONIC HCV INFECTED EGYPTIAN PATIENTS AND THEIR IMPACT ON THE RESPONSE TO PEGYLATED INTERFERON THERAPY

Treatment of patients with chronic hepatitis C with the current standard pegylated interferon (PEG-IFN) and ribavirin achieves overall response (SVR) rates of ~55%. A role of CD4+ CD25+ regulatory T cells (Treg cells) has been proposed as they can suppress HCV-specific T cells in HCV-infected patien...

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Principais autores: ZEINAB SHAKER, SUHER ZADA, MOHAMED EL-REFAIY, WALID AHMADI, MOHAMED EL KHASHAB, MAGED EL GHANNAM, MONA ZOHEIRY, FATEN NAGY, EMAN EL-AHWANY
Format: Artigo
Sprog:Inglês
Udgivet: The Egyptian Society of Parasitology 2015-08-01
Serier:Journal of the Egyptian Society of Parasitology
Fag:
T Regulatory cells
Chronic HCV
Pegylated interferon
Ribavirin
Chemokines- Cytokines
Online adgang:https://jesp.journals.ekb.eg/article_89917_0f152c48a46bff2e58e1d4f0adf73e14.pdf
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