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DESIGN AND OPTIMIZATION OF TOLMETIN SODIUM MICROSPHERES PREPARED BY EMULSIFICATION-INTERNAL GELATION USING RESPONSE SURFACE METHODOLOGY

In a trial to delay the release rate of tolmetin sodium from alginate coated microspheres, the use of a copolymer was suggested.  Mixtures of polymers can have a significant property than that of individual polymer to achieve controlled release microspheres.  A 32 factorial design was employed to pr...

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Auteur principal: Mahmoud Elsayed
Format: Artigo
Langue:Inglês
Publié: Al-Azhar University, Faculty of Pharmacy 2012-03-01
Collection:Al-Azhar Journal of Pharmaceutical Sciences
Accès en ligne:https://ajps.journals.ekb.eg/article_7249_686186c79d65b987c20912c186eb5a96.pdf
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