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Multi-omics reveals Dengzhan Shengmai formulation ameliorates cognitive impairments in D-galactose-induced aging mouse model by regulating CXCL12/CXCR4 and gut microbiota

Dengzhan Shengmai (DZSM), a traditional Chinese medicine formulation, has been administered extensively to elderly individuals with cognitive impairment (CI). However, the underlying mechanisms by which Dengzhan Shengmai improves cognitive impairment remains unknown. This study aimed to elucidate th...

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Principais autores: Jing-Yi Hou, He Xu, Guang-Zhao Cao, Liang-Liang Tian, Li-Han Wang, Nai-Qiang Zhu, Jing-Jing Zhang, Hong-Jun Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-04-01
Serier:Frontiers in Pharmacology
Fag:
Dengzhan Shengmai (DZSM)
cognitive impairment (CI)
aging
CXCR4
CXCL12
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2023.1175970/full
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