Prolonged visual experience accelerates developmental synaptic downscaling via epigenetic regulation and Rab5c mediated AMPA receptor trafficking

Abstract Environmental light significantly influences neural development, yet the specific mechanisms underlying the effects of prolonged visual experience on homeostatic synaptic scaling remain unclear. Using manipulated ambient light conditions, we observed reduced mEPSC amplitudes and visually ev...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Lijun Zheng, Xinyi Duan, Wenyi Huang, Yuhao Luo, Yufei Wu, Qihui Lin, Xiaohua Wu, Lu Han, Wanhua Shen
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2026-01-01
Sarja:	Communications Biology
Linkit:	https://doi.org/10.1038/s42003-025-09507-5
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