Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice

Progress in gene editing research has been accelerated by utilizing engineered nucleases in combination with induced pluripotent stem cell (iPSC) technology. Here, we report transcription activator-like effector nuclease (TALEN)-mediated reincorporation of Arg1 exons 7 and 8 in iPSCs derived from ar...

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Egile Nagusiak:	Yuan Yan Sin, Laurel L. Ballantyne, Christopher R. Richmond, Colin D. Funk
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2018-03-01
Saila:	Molecular Therapy: Nucleic Acids
Gaiak:	TALEN gene editing homology-directed repair arginase-1 deficiency hepatocyte-like cell transplant
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2162253117302962
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