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Structural basis of human cytomegalovirus neutralization by gB AD-5-specific potent antibodies

Summary: Human cytomegalovirus (hCMV) poses a severe threat to fetuses, newborns, and immunocompromised individuals. No approved vaccines and limited treatment options are current medical challenges. Here, we analyze the human B cell responses to glycoprotein B (gB) in three top hCMV neutralizers fr...

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Principais autores: Changwen Wu, Nan Song, Yizhen Zhao, Han Wang, Yuanbao Ai, Yayu Wang, Yueming Wang, Xiaohui Yuan, Tong Liu, Nan Li, Dabbu Kumar Jaijyan, Chengming Li, Lei Zhang, Weihong Zheng, Zhiwei Yang, Shujia Zhu, Hua-Xin Liao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-05-01
coleção:Cell Reports
Assuntos:
CP: Immunology
CP: Microbiology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124725004176
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