Case report: mismatch repair proficiency and microsatellite stability in gastric cancer may not predict programmed death-1 blockade resistance

Abstract Background Anti-programmed death-1 therapy has poor efficacy in mismatch repair-proficient (pMMR) colorectal cancers; however, its efficacy in pMMR gastric cancers remains undetermined. Here, we report the case of a patient with pMMR and microsatellite-stable gastric cancer who exhibited a...

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Autores principales:	Kuo-Hsing Chen, Chang-Tsu Yuan, Li-Hui Tseng, Chia-Tung Shun, Kun-Huei Yeh
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2016-03-01
Colección:	Journal of Hematology & Oncology
Materias:	Gastric cancer Immunotherapy Anti-programmed death-1 antibody Mismatch repair deficiency Mismatch repair proficiency Microsatellite stability
Acceso en línea:	http://link.springer.com/article/10.1186/s13045-016-0259-0
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