TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans
Although amyloid β (Aβ) and tau aggregates define the neuropathology of Alzheimer's disease (AD), TDP-43 has recently emerged as a co-morbid pathology in more than half of patients with AD. Individuals with concomitant Aβ, tau and TDP-43 pathology experience accelerated cognitive decline and worsene...
Na minha lista:
| Principais autores: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2022-04-01
|
| coleção: | Disease Models & Mechanisms |
| Assuntos: | |
| Acesso em linha: | http://dmm.biologists.org/content/15/4/dmm049323 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|