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Triethyl phosphate (TEP) as a green solvent for solid-phase peptide synthesis (SPPS)

Triethyl phosphate (TEP) is a new member of the Green Solid-Phase Peptide Synthesis (GSPPS) toolbox. TEP shows almost no toxicity and no carcinogenic or mutagenic properties. It degrades, giving the rather innocuous phosphoric acid and ethanol. TEP has a low viscosity, which makes it appealing for s...

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Autori principali: K.P. Nandhini, Nosipho Cele, Beatriz G. de la Torre, Fernando Albericio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2024-12-01
Serie:Green Chemistry Letters and Reviews
Soggetti:
Fluorenylmethoxycarbonyl (Fmoc)
green solvent
peptide
polystyrene resin
supported chemistry
Accesso online:https://www.tandfonline.com/doi/10.1080/17518253.2024.2330639
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