Structure–function insights reveal the human ribosome as a cancer target for antibiotics
The ribosome of bacteria and other unicellular pathogens is a common target for antibiotic drugs. Here the authors determine a structure of the human ribosome bound to the translation inhibitor cycloheximide, and provide evidence that targeting the ribosome is a promising avenue for cancer therapy.
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| Автори: | , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2016-09-01
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| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/ncomms12856 |
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