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Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma

BackgroundAberrant fatty acid metabolism (FAM) plays a critical role in the tumorigenesis of human malignancies. However, studies on its impact in lung adenocarcinoma (LUAD) are limited.MethodsWe developed a prognostic signature comprising 10 FAM-related genes (GPR115, SOAT2, CDH17, MOGAT2, COL11A1,...

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Principais autores: Denggang Fu, Biyu Zhang, Wenyan Fan, Fanfan Zeng, Jueping Feng, Xin Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-10-01
coleção:Frontiers in Immunology
Assuntos:
lung adenocarcinoma
fatty acid metabolism
prognosis
immune microenvironment
immunotherapy
MOGAT2
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1456719/full
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