Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India

Abstract Background Genes encoding dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) are the targets of sulfadoxine–pyrimethamine (SP) present in artemisinin based combination therapy (ACT; artesunate + sulfadoxine pyrimethamine) for Plasmodium falciparum. Although SP is generally n...

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Detalhes bibliográficos

Principais autores:	Shiny Joy, Susanta K. Ghosh, Rajeshwara N. Achur, D. Channe Gowda, Namita Surolia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-04-01
coleção:	Malaria Journal
Assuntos:	Dihydrofolate reductase Dihydropteroate synthase Single nucleotide polymorphisms Restriction fragment length polymorphisms Sulfadoxine/pyrimethamine Mangaluru
Acesso em linha:	http://link.springer.com/article/10.1186/s12936-018-2316-3
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