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From clinics to sewers: leveraging environmental surveillance and whole genome sequencing to inform transmission of ESBL-Escherichia coli in Switzerland

ABSTRACT Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-E. coli) is a major antimicrobial resistance concern spreading across human, animal, and environmental domains. To assess between-source transitions, we analyzed 762 ESBL-E. coli genomes collected from wastewater (used as a comm...

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Asıl Yazarlar: Sheena Conforti, Louis du Plessis, Claudia Bagutti, Jens Becker, Silvio D. Brugger, Alexia Cusini, Adrian Egli, Valeria Gaia, Gilbert Greub, Cornelia Guler, Jana S. Huisman, Claudine Kocher, Roger D. Kouyos, Karoline Leuzinger, Carola Maffioli, Mara Neacșu, Oliver Nolte, Alban Ramette, Salome N. Seiffert, Sarah Tschudin-Sutter, Jon Paulin Zumthor, Tanja Stadler, Timothy R. Julian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2026-05-01
Seri Bilgileri:Applied and Environmental Microbiology
Konular:
antimicrobial resistance
One Health
ESBL-E. coli
wastewater-based surveillance
phylogenetics
sequencing
Online Erişim:https://journals.asm.org/doi/10.1128/aem.01848-25
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