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Low Intestinal IL22 Associates With Increased Transplant-Related Mortality After Allogeneic Stem Cell Transplantation

The role of IL-22 in adult patients undergoing allogeneic stem cell transplantation (SCT) is of major interest since animal studies showed a protective and regenerative effect of IL-22 in graft versus host disease (GvHD). However, no clinical data exist on the tissue expression. Here we demonstrate...

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Principais autores: Sakhila Ghimire, Katharina U. Ederer, Elisabeth Meedt, Daniela Weber, Carina Matos, Andreas Hiergeist, Florian Zeman, Daniel Wolff, Matthias Edinger, Hendrik Poeck, Wolfgang Herr, André Gessner, Ernst Holler, Sigrid Bülow
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
coleção:Frontiers in Immunology
Assuntos:
IL22
allogeneic SCT
GvHD
TRM
antibiotics
GPR41
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.857400/full
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