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Pediatric Mini-Tablets: Predicting the Hidden Risk of Fill Errors

Compressed mini-tablets in sachets or capsules are an increasingly prevalent oral solid dosage form for pediatric products. While resembling adult tablets, additional care is required to control weight and potency (blend uniformity) variation due to their small size (≤2.5 mm average diameter). Addit...

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Autori principali: Brandon G. Gerberich, Grace A. Okoh, James C. DiNunzio, Michael B. Lowinger
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2023-02-01
Serie:Pharmaceutics
Soggetti:
mini-tablet
content uniformity
fill count
sachet
fill errors
dose uniformity
Accesso online:https://www.mdpi.com/1999-4923/15/2/594
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