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T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

Abstract We recently developed an immuno-oncotherapy against human papillomavirus (HPV)-induced tumors based on a lentiviral vector encoding the Early E6 and E7 oncoproteins of HPV16 and HPV18 genotypes, namely “Lenti-HPV-07”. The robust and long-lasting anti-tumor efficacy of Lenti-HPV-07 is depend...

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Autori principali: Ingrid Fert, Laëtitia Douguet, Benjamin Vesin, Fanny Moncoq, Amandine Noirat, Pierre Authié, Sylvain Ciret, Fabien Le Chevalier, Catherine Blanc, Yakov Vitrenko, Pierre Charneau, Laleh Majlessi, François Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-06-01
Serie:npj Vaccines
Accesso online:https://doi.org/10.1038/s41541-024-00894-0
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