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Random mutagenesis in <it>Corynebacterium glutamicum </it>ATCC 13032 using an IS<it>6100</it>-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway

<p>Abstract</p> <p>Background</p> <p><it>Corynebacterium glutamicum</it>, a Gram-positive bacterium of the class Actinobacteria, is an industrially relevant producer of amino acids. Several methods for the targeted genetic manipulation of this organism and rational strain improvement have been devel...

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Autori principali: Gaigalat Lars, Rückert Christian, Lömker Alexander, Mormann Sascha, Tauch Andreas, Pühler Alfred, Kalinowski Jörn
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2006-08-01
Serie:BMC Genomics
Accesso online:http://www.biomedcentral.com/1471-2164/7/205
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