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Tumor-associated CD8+T cell tolerance induced by erythroid progenitor cells

IntroductionCD8+T cell tolerance plays an important role in tumor escape. Recent studies have shown that CD45+ erythroid progenitor cells (CD45+EPCs) generated through splenic extramedullary erythropoiesis suppress tumor immunity. However, the mechanism underlying how CD45+EPCs mediate CD8+T cell to...

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Bibliographic Details
Main Authors: Xue Fan, Han Peng, Xuesong Wang, Yixin Sun, Yan Dong, Jie Zhou, Jianfang Chen, Shuo Huang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1381919/full
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