Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways.

Lymphatic vessels play an important role in health and in disease. In this study, we evaluated the effects of GSK3-β inhibition on lung lymphatic endothelial cells in vitro. Pharmacological inhibition and silencing of GSK3-β resulted in increased lymphangiogenesis of lung lymphatic endothelial cells...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Benjamin Stump, Shikshya Shrestha, Anthony M Lamattina, Pierce H Louis, Woohyun Cho, Mark A Perrella, Xingbin Ai, Ivan O Rosas, Florence F Wagner, Carmen Priolo, Jonathan Astin, Souheil El-Chemaly
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Public Library of Science (PLoS) 2019-01-01
Cyfres:	PLoS ONE
Mynediad Ar-lein:	https://doi.org/10.1371/journal.pone.0213831
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!