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Synergistic intravesical instillation for bladder cancer: CRISPR-Cas13a and fenbendazole combination therapy

Abstract Background CRISPR-Cas13a is renowned for its precise and potent RNA editing capabilities in cancer therapy. While various material systems have demonstrated efficacy in supporting CRISPR-Cas13a to execute cellular functions in vitro efficiently and specifically, the development of CRISPR-Ca...

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Principais autores: Mingkang Liang, Yongqiang Wang, Lisha Liu, Dashi Deng, Zeqin Yan, Lida Feng, Chenfan Kong, Chenchen Li, Yuqing Li, Guangzhi Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
CRISPR-Cas13a
Flubendazole
Fluorinated chitosan
Bladder cancer
Programmed death ligand 1
Transmembrane peptides
Online adgang:https://doi.org/10.1186/s13046-024-03146-0
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