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Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses.

Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including uncontrolled viral replication, infection of the lower airway, and highly inflammatory cytokine responses have been extensively documented, the...

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Príomhchruthaitheoirí: Peter S Askovich, Catherine J Sanders, Carrie M Rosenberger, Alan H Diercks, Pradyot Dash, Garnet Navarro, Peter Vogel, Peter C Doherty, Paul G Thomas, Alan Aderem
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2013-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC3779241?pdf=render
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