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The Effect of ASIC3 Knockout on Corticostriatal Circuit and Mouse Self-grooming Behavior

Stereotypic and/or repetitive behavior is one of the major symptoms of autism spectrum disorder (ASD). Increase of self-grooming behavior is a behavioral phenotype commonly observed in the mouse models for ASD. Previously, we have shown that knockout of acid-sensing ion channel 3 (ASIC3) led to the...

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Autores principales: Wei-Li Wu, Sin-Jhong Cheng, Shing-Hong Lin, Yu-Chia Chuang, Eagle Yi-Kung Huang, Chih-Cheng Chen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019-03-01
Colección:Frontiers in Cellular Neuroscience
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Acceso en línea:https://www.frontiersin.org/article/10.3389/fncel.2019.00086/full
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