The Influence of Copy Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense
Prokaryotic type I CRISPR-Cas systems respond to the presence of mobile genetic elements such as plasmids and phages in two different ways. CRISPR interference efficiently destroys foreign DNA harbouring protospacers fully matching CRISPR RNA spacers. In contrast, even a single mismatch between a sp...
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| Автори: | , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Frontiers Media S.A.
2016-08-01
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| Серія: | Frontiers in Molecular Biosciences |
| Предмети: | |
| Онлайн доступ: | http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00045/full |
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