Design, Synthesis, and Biological Evaluation of N-Acyl-Homoserine Lactone Analogs of Quorum Sensing in Pseudomonas aeruginosa

Quorum sensing plays a necessary role in the production of virulence factors and the formation of biofilm on Pseudomonas aeruginosa. Thus, the development of inhibition of quorum sensing is one of the most promising methods to control bacterial infection and antibiotic resistance. In this work, nine...

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Principais autores:	Zhenyu Wei, Ting Li, Yan Gu, Qian Zhang, Enhui Wang, Wenbo Li, Xin Wang, Yang Li, Hongyu Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-07-01
Colecção:	Frontiers in Chemistry
Assuntos:	AHL analogs quorum sensing Pseudomonas aeruginosa anti-virulence antibiofilm
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fchem.2022.948687/full
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