Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

ABSTRACT NUMB is an endocytic protein with tumor suppressor activity, largely mediated by its ability to inhibit p53 degradation. This function depends on the inclusion of a short alternatively spliced exon (Ex3) in NUMB, although the mechanistic link between endocytosis and p53 regulation remains u...

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Κύριοι συγγραφείς:	Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Wiley 2026-05-01
Σειρά:	Advanced Science
Θέματα:	exosomes non‐cell‐autonomous NUMB p53 SNX9
Διαθέσιμο Online:	https://doi.org/10.1002/advs.202513765
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