Single‐cell RNA sequencing reveals cell immune status and dysregulated monocytes in patients with myasthenia gravis

Abstract Objectives As an autoimmune disorder, myasthenia gravis (MG) manifests as an autoimmune attack on postsynaptic neuromuscular junction proteins by pathogenic autoantibodies. This immune attack disrupts neurotransmission, resulting in fatigable skeletal muscle weakness with diurnal fluctuatio...

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Bibliografische Detailangaben

Hauptverfasser:	Yufan Guo, Yu Gu, Yuting Jin, Xintao Wu, Yuting Lou, Pu Miao, Ye Wang, Bijun Zhang, Xueting Lin, Chudi Zhang, Jianhua Feng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2025-01-01
Schriftenreihe:	Clinical & Translational Immunology
Schlagworte:	CD14+FOS+ monocyte CD14+S100A12+ monocyte inflammation myasthenia gravis scRNA‐seq
Online-Zugang:	https://doi.org/10.1002/cti2.70052
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