Balanced crystalloids vs. 0.9% saline in pediatric diabetic ketoacidosis: a systematic review and meta-analysis of randomized controlled trials

BackgroundFluid resuscitation is a cornerstone in the management of pediatric diabetic ketoacidosis (DKA). While 0.9% normal saline (NS) remains the conventional first-line fluid, concerns regarding its high chloride content and potential to induce hyperchloremic metabolic acidosis have led to incre...

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Principais autores:	Zeid Alkhairi, Charlie Kajo, Abdolaziz A. Zadeh, Dawood Khaja, Mohammad Alqaryuti, Nada K. Alsaleh, Rataj Alibrahim, Fahad Almuhannadi, Suod Al Hammad, Fatima Alqanea, Abdullatif Alfehaid
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-07-01
Series:	Frontiers in Pediatrics
Assuntos:	acute kidney injury balanced crystalloids diabetic ketoacidosis normal saline pediatric plasma-lyte
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fped.2026.1879829/full
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