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Influence of PTPN22 Allotypes on Innate and Adaptive Immune Function in Health and Disease

Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) regulates a panoply of leukocyte signaling pathways. A single nucleotide polymorphism (SNP) in PTPN22, rs2476601, is associated with increased risk of Type 1 Diabetes (T1D) and other autoimmune diseases. Over the past decade PTPN22 has been...

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Váldodahkkit: Lucas H. Armitage, Mark A. Wallet, Clayton E. Mathews
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2021-02-01
Ráidu:Frontiers in Immunology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636618/full
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