Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival in Dictyostelium

ABSTRACT Human macrophages and the eukaryotic microbe Dictyostelium discoideum ingest bacteria by phagocytosis, and then kill the ingested bacteria. Some pathogenic bacteria secrete linear chains of phosphate residues (polyphosphate; polyP), and the polyP prevents some of the phagocytes from killing...

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Váldodahkkit:	Ryan J. Rahman, Ramesh Rijal, Shiyu Jing, Te-An Chen, Issam Ismail, Richard H. Gomer
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	American Society for Microbiology 2023-10-01
Ráidu:	mBio
Fáttát:	polyphosphate Dictyostelium phagocytosis bacterial survival
Liŋkkat:	https://journals.asm.org/doi/10.1128/mbio.01939-23
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