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Tunable, biodegradable grafting-from glycopolypeptide bottlebrush polymers

Synthetic mimics of glycoproteins and proteoglycans have wide applications in biomedicine, yet preparation has been challenged by their high grafting and glycosylation densities. Here the authors show one-pot dual-catalysis polymerization of glycan-bearing α-amino acid N-carboxyanhydrides to form gl...

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Principais autores: Zachary S. Clauss, Casia L. Wardzala, Austin E. Schlirf, Nathaniel S. Wright, Simranpreet S. Saini, Bibiana Onoa, Carlos Bustamante, Jessica R. Kramer
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2021-11-01
叢編:Nature Communications
在線閱讀:https://doi.org/10.1038/s41467-021-26808-5
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