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Streptococcus pyogenes Sortase Mutants Are Highly Susceptible to Killing by Host Factors Due to Aberrant Envelope Physiology.

Cell wall anchored virulence factors are critical for infection and colonization of the host by Gram-positive bacteria. Such proteins have an N-terminal leader sequence and a C-terminal sorting signal, composed of an LPXTG motif, a hydrophobic stretch, and a few positively charged amino acids. The s...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Assaf Raz, Ana-Maria Tanasescu, Anna M Zhao, Anna Serrano, Tricia Alston, Asaf Sol, Gilad Bachrach, Vincent A Fischetti
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2015-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://doi.org/10.1371/journal.pone.0140784
Tagiau: Ychwanegu Tag
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