Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a two-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus artesunate monotherapy among asymptomatic children 3–5 years of age in Zambia

Abstract Background The 2022 malaria chemoprevention guidelines of the World Health Organization (WHO) recommend the provision of a full treatment course of an antimalarial medicine at predefined intervals, regardless of whether the child is infected with malaria, to prevent illness in moderate to h...

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Hauptverfasser:	Rosario Martinez-Vega, Mike Chaponda, Andria Mousa, Jonathan Gwasupika, Enesia Banda Chaponda, Victor Daka, Sydney Mwanza, Mukuka Chipunga, Khalid B. Beshir, Ana Chopo-Pizarro, Harparkash Kaur, Lucy Okell, Helle Hansson, Emma Filtenborg Hocke, Michael Alifrangis, Roland Gosling, Cally Roper, Colin Sutherland, R. Matthew Chico
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-11-01
Schriftenreihe:	BMC Infectious Diseases
Schlagworte:	Perennial malaria chemoprevention Intermittent preventive treatment Antimalarial resistance
Online-Zugang:	https://doi.org/10.1186/s12879-025-11975-3
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